Metabolic Profiling of Plasma and Synovial Fluid

Blood samples were collected after overnight fast of at least 8 h, and SF samples were collected during joint replacement surgeries. Plasma and SF samples were processed as previous described [7 ]. Metabolic profiling in both plasma and SF were performed by the Waters XEVO TQ MS system (Waters Ltd.) using the Biocrates AbsoluteIDQ p180 kit as part of a previous project [18 (link)]. Data on PC ae C34:3 and PC ae C36:3 were retrieved from the metabolic profile data for the purposes of the current study.

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Zhang W., Randell E.W., Sun G., Likhodii S., Liu M., Furey A, & Zhai G. (2017). Hyperglycemia-related advanced glycation end-products is associated with the altered phosphatidylcholine metabolism in osteoarthritis patients with diabetes. PLoS ONE, 12(9), e0184105.

Publication 2017

XEVO TQ MS system AbsoluteIDQ p180 kit

Blood Joint replacement surgeries Metabolic profile Plasma

Corresponding Organization : University of Tasmania

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Variable analysis

independent variables

None explicitly mentioned

dependent variables

PC ae C34:3
PC ae C36:3

control variables

Overnight fast of at least 8 h
Joint replacement surgeries

controls

No positive or negative controls were explicitly mentioned in the provided information.

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