Carbon Ion Radiotherapy Protocol for Prostate Cancer

Patients received CIRT at QST Hospital, Japan, according to a comprehensive treatment protocol reported previously [12 (link),13 (link),14 (link),15 (link)]. CIRT targeting the prostate gland and seminal vesicle was administered once a day for 4 days per week. The radiation dose was measured in Gy (RBE) (physical carbon ion dose [Gy] × RBE). The RBE value for CIRT was estimated as 3.0 at the distal portion of the spread-out Bragg peak in prior investigations [12 (link),13 (link),14 (link),15 (link)]. The following dose fractionation scheme was employed in this study: 63.0 Gy (RBE) administered over 20 fractions (77 cases), 57.6 Gy (RBE) administered over 16 fractions (298 cases), and 51.6 Gy (RBE) administered over 12 fractions (295 cases).

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Utsumi T., Suzuki H., Ishikawa H., Wakatsuki M., Okonogi N., Harada M., Ichikawa T., Akakura K., Murakami Y., Tsuji H, & Yamada S. (2023). Identification of Early Biochemical Recurrence Predictors in High-Risk Prostate Cancer Patients Treated with Carbon-Ion Radiotherapy and Androgen Deprivation Therapy. Current Oncology, 30(10), 8815-8825.

Publication 2023

Carbon Cirt Dose fractionation Patients Physical Prostate gland Radiation Seminal vesicle Treatment protocol

Corresponding Organization : National Institutes for Quantum and Radiological Science and Technology

Other organizations : Toho University Medical Center Sakura Hospital, Toho University, Chiba University, Tokyo Yamate Medical Center

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Variable analysis

independent variables

Radiation dose fractionation scheme

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control variables

Patients received CIRT at QST Hospital, Japan
CIRT targeting the prostate gland and seminal vesicle was administered once a day for 4 days per week
The RBE value for CIRT was estimated as 3.0 at the distal portion of the spread-out Bragg peak in prior investigations

controls

Positive controls not explicitly mentioned
Negative controls not explicitly mentioned

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