FDG PET/CT scans were obtained from a subset of patients before, during, and at the end of CRT (after the delivery of 40–50 Gy), and for 4 months post-CRT. All patients fasted for a minimum of 6 hours to achieve a blood glucose level of 80–120 mg/dL (4.4-6.6 mmol/L) before intravenous administration of FDG (555-740 MBq [15-20 mCi]). Data were acquired with a GE Discovery ST PET/CT scanner 60 minutes after radiotracer injection, with 3 minutes per bed in 2D acquisition mode, from orbit to mid-thigh.
PET/CT images were processed and evaluated by a clinical investigator and an experienced nuclear medicine physician using Mirada XD3 software (Mirada Medical, Denver, CO), which automatically generated normal-lung SUVmean values [19 (link)].
PET/CT images were processed and evaluated by a clinical investigator and an experienced nuclear medicine physician using Mirada XD3 software (Mirada Medical, Denver, CO), which automatically generated normal-lung SUVmean values [19 (link)].
