Pituitary FSHR Knockdown in Adrenalectomized Mice
Corresponding Organization :
Other organizations : Saarland University, Xi'an University of Science and Technology, Max Planck Institute of Biophysics, McGill University, University of Liège, Institut de Génomique Fonctionnelle
Variable analysis
- Administration of AAV virus (AAV5-saCas9-Fshr) into the pituitary
- Expression of Fshr gene
- Progression of post-surgical complications to the defined humane endpoint
- Bilateral adrenalectomy in wild-type adult female mice
- Maintenance of salt levels through 0.9% saline administration
- No positive controls were explicitly mentioned.
- The negative control was the wild-type adult female mice that underwent bilateral adrenalectomy.
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