The ontology includes the major cell types from the major model organisms (for example, human, mouse, Drosophila, Caenorhabditis, zebrafish, Dictyostelium discoideum, Arabidopsis, fungi and prokaryotes). These cell types have been collated from our own knowledge, from major textbooks (for example [20 -22 ]), from the embryo and anatomy ontologies available on the OBO site [7 ], and from colleagues (who are thanked in the acknowledgements). The ontology currently holds some 680 cell types, together with their synonyms and, in most cases, text definitions.
The ontology was constructed using the open source Java tool OBO-Edit (previously known as DAG-Edit) [23 ], which is convenient for building ontologies that are consistent with the GO formalism. The resulting ontology is available in both the GO 'flat-file' format [24 ] and the newly defined 'OBO format' [25 ], and can easily be viewed using the OBO-Edit or the COBrA open source Java tool [26 ].
The ontology was constructed using the open source Java tool OBO-Edit (previously known as DAG-Edit) [23 ], which is convenient for building ontologies that are consistent with the GO formalism. The resulting ontology is available in both the GO 'flat-file' format [24 ] and the newly defined 'OBO format' [25 ], and can easily be viewed using the OBO-Edit or the COBrA open source Java tool [26 ].
Free full text: Click here
