19 (link) NT‐proBNP (N‐terminal pro‐B‐type natriuretic peptide) was measured using an electrochemiluminescent immunoassay on an automated Cobas e411 analyzer (Roche Diagnostics, Mannheim, Germany), and high‐sensitivity cardiac troponin T levels were measured with a highly sensitive assay, Elecsys Troponin T (Roche Diagnostics, Indianapolis, IN) on an automated Cobas e411 analyzer. CRP (C‐reactive protein) was measured via immunophelometric assay.
Cardiometabolic Risk Biomarker Profiling
19 (link) NT‐proBNP (N‐terminal pro‐B‐type natriuretic peptide) was measured using an electrochemiluminescent immunoassay on an automated Cobas e411 analyzer (Roche Diagnostics, Mannheim, Germany), and high‐sensitivity cardiac troponin T levels were measured with a highly sensitive assay, Elecsys Troponin T (Roche Diagnostics, Indianapolis, IN) on an automated Cobas e411 analyzer. CRP (C‐reactive protein) was measured via immunophelometric assay.
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Corresponding Organization :
Other organizations : Johns Hopkins University, Johns Hopkins Medicine, University of Minnesota, University of Miami, Houston Methodist, Baylor College of Medicine
Variable analysis
- Medical history
- Medication use
- Alcohol use
- Current smoking
- Systolic BP
- Diastolic BP
- Body mass index
- Obesity
- Serum glucose
- Plasma glucose
- Serum triglycerides
- High-density lipoprotein cholesterol
- NT-proBNP
- High-sensitivity cardiac troponin T
- Standardized self-report questionnaires
- Mean of 2 BP readings
- Hexokinase method for glucose measurement
- Automated enzymatic assays for lipid measurements
- Serum creatinine and cystatin C-based equation for eGFR
- Electrochemiluminescent immunoassay for NT-proBNP
- Highly sensitive assay for high-sensitivity cardiac troponin T
- Immunophelometric assay for CRP
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