All participants underwent an ultrasonographic scan of the liver, performed by a single sonographer (Siemens Antares ultrasound machine with a CH 2- to 5-MHz convex probe). Then, a radiologist (specialized in liver imaging and blinded to the clinical and laboratory findings of the subjects) interpreted the ultrasound images. NAFLD was diagnosed using ultrasonographic scoring for liver steatosis and the findings of fatty infiltration (liver echotexture, echo penetration, and clarity of vessel structures) [15 (link)].
Subjects with the suggested NAFLD by ultrasonography were confirmed by MR imaging with a standard torso phased-array coil centered over the liver at 3-T MR imager (Signa Excite HD; GE Medical Systems, Milwaukee, WI; eight-channel coil). Two experienced radiologists reviewed images through Osirix and estimated the liver proton density fat fraction (PDFF), which is a measure of liver fat content [16 (link)].
Subjects with the suggested NAFLD by ultrasonography were confirmed by MR imaging with a standard torso phased-array coil centered over the liver at 3-T MR imager (Signa Excite HD; GE Medical Systems, Milwaukee, WI; eight-channel coil). Two experienced radiologists reviewed images through Osirix and estimated the liver proton density fat fraction (PDFF), which is a measure of liver fat content [16 (link)].
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