As previously described (Boman et al, 2013b (link)), the tissue from the cohorts (described above) were retrospectively collected for the production of the TMA (cohorts I and II). Representative tissue areas were identified by pathologist, classifying the tumours according to the WHO grading system of 2004 (Sauter et al, 2004 ). In addition, the TMA was constructed using an automated instrument, ATA-27 (Beecher Instruments, Sun Prairie, WI, USA). All tissue samples were represented in duplicate tissue cores (1 mm).
Protocol detail
Retrospective Collection of Tissue Samples for TMA
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Pathologist
Tissue
Tumours
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Variable analysis
independent variables
- Tissue samples from the cohorts (described above)
- Classification of tumors according to the WHO grading system of 2004
- Tissue samples were represented in duplicate tissue cores (1 mm)
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