Navigational Guidance for Glioma Resection

All glioma resections were performed with navigational guidance (Stealth Station Cranial Treon or S7; Medtronic, CO, USA) using T1-contrast-enhanced MRI co-registered with PET_max or CSI_max as described elsewhere [11] , [17] (link). Depending on tumor location, additional functional imaging data from fMRI and DTI were used as appropriate. The following protocol was applied for tissue sampling and assessment of potential PpIX fluorescence during each glioma resection:

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Widhalm G., Kiesel B., Woehrer A., Traub-Weidinger T., Preusser M., Marosi C., Prayer D., Hainfellner J.A., Knosp E, & Wolfsberger S. (2013). 5-Aminolevulinic Acid Induced Fluorescence Is a Powerful Intraoperative Marker for Precise Histopathological Grading of Gliomas with Non-Significant Contrast-Enhancement. PLoS ONE, 8(10), e76988.

Publication 2013

Cranial Fluorescence Fmri Glioma Ppix Tissue Tumor location

Corresponding Organization : Medical University of Vienna

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Protocol cited in 4 other protocols

Variable analysis

independent variables

Navigational guidance (Stealth Station Cranial Treon or S7; Medtronic, CO, USA)
T1-contrast-enhanced MRI co-registered with PET_max or CSI_max
Functional imaging data from fMRI and DTI

dependent variables

Potential PpIX fluorescence during each glioma resection

control variables

Tumor location

positive controls

No positive controls specified

negative controls

No negative controls specified

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