Quinoline and its derivatives were
hydrogenated by the transfer hydrogen (TH) reaction, using water as
a green solvent. The experiments were conducted in a Teflon-capped
10 mL glass reaction tube placed in a reactor, which is capable of
running 10 parallel reactions simultaneously. The conditions were
as follows: quinoline (0.5 mmol, 59 μL), Pd@Fe3O4 catalyst (5 mg), and 10 mL of deionized water were added
into a reaction tube. Then, THDB (2 mmol, 179 mg) was added to the
suspension and stirred at 80 °C with a stirring speed of 250
rpm. The progress of the reaction was monitored by thin-layer chromatography
(TLC) and gas chromatography–mass spectrometry (GC-MS). After
completion of the reaction, the product was extracted with chloroform
(3 × 5 mL), combined with organic layers, dried with sodium sulfate,
and then filtered through a short column packed with silica gel. The
product was taken up for GC to measure the conversion and selectivity
and identified by its molecular ion peak (m/z) detected in GC-MS.
hydrogenated by the transfer hydrogen (TH) reaction, using water as
a green solvent. The experiments were conducted in a Teflon-capped
10 mL glass reaction tube placed in a reactor, which is capable of
running 10 parallel reactions simultaneously. The conditions were
as follows: quinoline (0.5 mmol, 59 μL), Pd@Fe3O4 catalyst (5 mg), and 10 mL of deionized water were added
into a reaction tube. Then, THDB (2 mmol, 179 mg) was added to the
suspension and stirred at 80 °C with a stirring speed of 250
rpm. The progress of the reaction was monitored by thin-layer chromatography
(TLC) and gas chromatography–mass spectrometry (GC-MS). After
completion of the reaction, the product was extracted with chloroform
(3 × 5 mL), combined with organic layers, dried with sodium sulfate,
and then filtered through a short column packed with silica gel. The
product was taken up for GC to measure the conversion and selectivity
and identified by its molecular ion peak (m/z) detected in GC-MS.
