Operant Conditioning for Amphetamine Studies

Lever press training, AMP self-administration and AMP-seeking tests were conducted in standard operant conditioning chambers (ENV-001, Med Associates, St. Albans, VT, USA) enclosed in a sound-attenuating and ventilated cubicle. AMP or SAL infusions were administered via a syringe pump (PHM-100, Med Associates) connected to a 10-ml syringe (Arndt, Garcia, et al., 2015 ;Arndt, Johns, et al., 2015 (link); Garcia et al., 2019 (link); Garcia & Cain, 2020 (link)).

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Garcia E.J, & Cain M.E. (2021). Isolation housing elevates amphetamine seeking independent of nucleus accumbens glutamate receptor adaptations. The European journal of neuroscience, 54(7), 6382-6396.

Publication 2021

ENV-001 PHM-100

Cain Self administration Sound Syringe

Corresponding Organization : Kansas State University

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Variable analysis

independent variables

AMP (amphetamine) infusion
SAL (saline) infusion

dependent variables

Lever press training
AMP self-administration
AMP-seeking tests

control variables

Standard operant conditioning chambers (ENV-001, Med Associates, St. Albans, VT, USA)
Sound-attenuating and ventilated cubicle
Syringe pump (PHM-100, Med Associates) connected to a 10-ml syringe (Arndt, Garcia, et al., 2015; Arndt, Johns, et al., 2015; Garcia et al., 2019; Garcia & Cain, 2020)

controls

SAL (saline) infusion

Annotations

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