C57BL/6J and IL-1R1−/− mice were obtained from Jackson Laboratory. The IL-36α−/− and IL-36α−/−/IL-1R1−/− mice have previously been described by us [6 (link)]. Wild type (C57BL/6J) and IL-1R1−/− mice for experiments involving IL-36α−/− and IL-36α−/−/IL-1R1−/− mice were bred in-house. All procedures were approved by the Temple University Institutional Animal Care and Use Committee.
Free full text: Click here