This study began after obtaining the study approval from the ethics committee of our hospital (Ethics committee decision no. 2021.04.35; dated: April 28, 2021). The study was conducted retrospectively and in a single center. The study was conducted between May 1, 2021, and May 1, 2022, with patients who were admitted to the emergency department with abdominal pain, diagnosed with AA, and met the criteria for inclusion in the study. Demographic data, medical history, WBC, platelet count, neutrophil count, SIII values, Alvarado scores, AAS, and pathology results of appendectomy material were retrieved from the hospital automation system [Hospital Information Management System (HIMS)] and recorded in the case form. The Alvarado score is a diagnostic score that is based on the symptoms (migratory pain, anorexia, nausea, and/or vomiting), signs (tenderness, rebound tenderness, and elevated body temperature), and laboratory findings (leukocytosis and left shift). One point was given to the presence of each indicator, except 2 points for tenderness and leukocytosis, making a total score of 10. AA cases were divided into two groups as complicated appendicitis and non-complicated appendicitis based on the presence of complications (gangrenous, perforated, and abscess formation). The study included 150 confirmed cases of AA and 150 control cases who were admitted to the emergency department with abdominal pain and not diagnosed with AA.
Study group patients with confirmed AA diagnosis and control group patients who were not diagnosed with AA after being admitted to the emergency department with abdominal pain were included in the study. In all, 3 patients under the age of 18 years, 5 pregnant patients, and 12 patients with missing data were excluded from the study. Also, 10 patients whose outcome could not be followed and whose medical history was unknown were not included in the study. In addition, 12 patients with any medical history of malignancy, a history of hematological disease, bone marrow pathology, and those taking anti-inflammatory or immunosuppressive drugs were also excluded from the study. In addition, patients with non-appendicitis infection focus were excluded from the study.
Study group patients with confirmed AA diagnosis and control group patients who were not diagnosed with AA after being admitted to the emergency department with abdominal pain were included in the study. In all, 3 patients under the age of 18 years, 5 pregnant patients, and 12 patients with missing data were excluded from the study. Also, 10 patients whose outcome could not be followed and whose medical history was unknown were not included in the study. In addition, 12 patients with any medical history of malignancy, a history of hematological disease, bone marrow pathology, and those taking anti-inflammatory or immunosuppressive drugs were also excluded from the study. In addition, patients with non-appendicitis infection focus were excluded from the study.
