All patients aged 60 and above who were undergoing alloBMT for a hematologic malignancy between July 2019 and March 2020 at one academic institution were offered participation in a non-therapeutic observational study (NCT04188678). This parent study, REBOUND, evaluates physical resilience in older adults receiving a stem cell transplant and involves physical function assessments, questionnaires about general health, cognitive assessments, personality/psychological assessments, and physiologic measures of blood, saliva, glucose tolerance, heart rate variability, and MRI collected during clinical visits. The parent study does not offer any intervention and does not intend to improve personal resilience or transplant survival. Only those who could not walk independently or speak English fluently were excluded from the parent study. Demographic, clinical data, and survivorship data were collected on all participants that were approached for enrollment. Characteristics and outcomes were compared between two groups: 1) those who elected to participate in the non-therapeutic parent study and 2) those who declined enrollment in the parent study but underwent alloBMT during the same time period at the same institution. This study was approved by the Johns Hopkins Institutional Review Board (IRB# 00,279,188).
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