We defined a TB patient as any person living with HIV and at least one specimen culture positive for Mycobacterium tuberculosis (MTB). We defined participants as having no TB if cultures were negative for MTB and participants were judged not to have TB on the basis of the original study definition of the investigators. We excluded from the analysis: (1) patients who were receiving treatment for TB (infection or disease) at enrolment; (2) patients who were AFB smear positive, but whose culture grew non-tuberculous mycobacteria; and (3) patients who were AFB smear positive or scanty, but sputum culture negative.
Getahun H., Kittikraisak W., Heilig C.M., Corbett E.L., Ayles H., Cain K.P., Grant A.D., Churchyard G.J., Kimerling M., Shah S., Lawn S.D., Wood R., Maartens G., Granich R., Date A.A, & Varma J.K. (2011). Development of a Standardized Screening Rule for Tuberculosis in People Living with HIV in Resource-Constrained Settings: Individual Participant Data Meta-analysis of Observational Studies. PLoS Medicine, 8(1), e1000391.
Corresponding Organization : World Health Organization
Other organizations :
Ministry of Public Health, Centers for Disease Control and Prevention, London School of Hygiene & Tropical Medicine, University of Zambia, Aurum Institute, Bill & Melinda Gates Foundation, Albert Einstein College of Medicine, Desmond Tutu HIV Foundation, University of Cape Town
Patients receiving treatment for TB (infection or disease) at enrolment
Patients who were AFB smear positive, but whose culture grew non-tuberculous mycobacteria
Patients who were AFB smear positive or scanty, but sputum culture negative
controls
Not explicitly mentioned
Not explicitly mentioned
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