Six months after the extraction, another CT and X-ray were performed to compare with the initial ones. The patient was anesthetized, and the crestal incision was made. A bone sample for histologic analysis purposes was taken with a surgical trephine drill of 3-mm diameter and 10-mm length used vertically in an occlusal-apical direction. After this step, titanium implants were finally placed according to the manufacturer (conical dental implant C1, MIS Implants Technologies Ltd., NC, USA). The wound was closed with a pedicle rotated soft tissue graft from the palate, sutured with a 4–0-thickness PROLENE™ polypropylene suture (Ethicon®, Johnson & Johnson, NJ, USA), and another radiograph was performed. The sequence of major events for a DEXGEL Bone group volunteer is depicted in Fig. 3.

Clinical images illustrating the procedures sequentially ordered from tooth extraction to dental implant placement

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