SARS-CoV-2 Testing of Hospital Staff

Oxford University Hospitals offer SARS-CoV-2 testing to all symptomatic and asymptomatic staff working at four teaching hospitals in Oxfordshire, United Kingdom. SARS-CoV-2 PCR testing of combined nasal and oropharyngeal swab specimens for symptomatic staff (those with new persistent cough, temperature ≥37.8°C, or anosmia or ageusia) was offered beginning on March 27, 2020. Asymptomatic health care workers were invited to participate in voluntary nasal and oropharyngeal swab PCR testing every 2 weeks and serologic testing every 2 months (with some participating more frequently for related studies) beginning on April 23, 2020, as previously described.^{5 ,22 (link)} Staff were followed until November 30, 2020. Deidentified data were obtained from the Infections in Oxfordshire Research Database, which has generic research ethics committee, Health Research Authority, and Confidentiality Advisory Group approvals.

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Lumley S.F., O’Donnell D., Stoesser N.E., Matthews P.C., Howarth A., Hatch S.B., Marsden B.D., Cox S., James T., Warren F., Peck L.J., Ritter T.G., de Toledo Z., Warren L., Axten D., Cornall R.J., Jones E.Y., Stuart D.I., Screaton G., Ebner D., Hoosdally S., Chand M., Crook D.W., O’Donnell A.M., Conlon C.P., Pouwels K.B., Walker A.S., Peto T.E., Hopkins S., Walker T.M., Jeffery K, & Eyre D.W. (2020). Antibody Status and Incidence of SARS-CoV-2 Infection in Health Care Workers. The New England Journal of Medicine.

Publication 2020

Ageusia Cough Generic Health care workers Infections Nasal Oropharyngeal Research ethics committee Sars cov 2

Corresponding Organization :

Other organizations : National Institute for Health Research, Oxford University Clinical Research Unit

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Variable analysis

independent variables

SARS-CoV-2 PCR testing of combined nasal and oropharyngeal swab specimens for symptomatic staff (those with new persistent cough, temperature ≥37.8°C, or anosmia or ageusia) offered beginning on March 27, 2020
Voluntary nasal and oropharyngeal swab PCR testing every 2 weeks and serologic testing every 2 months for asymptomatic health care workers (with some participating more frequently for related studies) beginning on April 23, 2020

dependent variables

SARS-CoV-2 infection status of symptomatic and asymptomatic staff

control variables

Staff were followed until November 30, 2020

controls

No positive or negative controls were explicitly mentioned in the provided information.

Annotations

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