Atomoxetine Effects on Rat Behavior

A single cohort of rats (n = 11) was used to test the effects of Atomoxetine (selective norepinephrine reuptake inhibitor). Atomoxetine (Tocris Bioscience) was prepared in 50:50 DMSO and 0.9% saline and administered i.p. (Baarendse et al. 2013 (link)).

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Blaes S.L., Orsini C.A., Mitchell M.R., Spurell M.S., Betzhold S.M., Vera K., Bizon J.L, & Setlow B. (2018). Monoaminergic modulation of decision making under risk of punishment in a rat model. Behavioural pharmacology, 29(8), 745-761.

Publication 2018

Atomoxetine

0 9 saline Atomoxetine Dmso Norepinephrine Rats

Corresponding Organization : University of Florida

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Variable analysis

independent variables

Atomoxetine (selective norepinephrine reuptake inhibitor)

dependent variables

Measured outcomes

control variables

Cohort size (n = 11)
Route of administration (i.p.)
Vehicle (50:50 DMSO and 0.9% saline)

controls

No positive or negative controls were explicitly mentioned in the provided information.

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