Endometrial Tumor Gene Expression Analysis

Gene expression data were downloaded from TCGA data repository as level 3 RNA sequence data [4 (link)] created by Illumina RNA Sequencer HiSeq 2000 platforms (Illumina Inc) and annotated with the HG-19 version of the human genome. Normalized and log-transformed gene expression data from these endometrial tumors were available for analysis. Analyses were performed with R statistical packages (R Foundation) for statistical computing and graphics [24 ] and bioconductor packages as open-source software for bioinformatics [25 (link)]. For the front end, we used Biometric Research Branch Array Tools, an integrated package for visualization and statistical analysis that uses Excel (Microsoft Corp) [26 (link)].