In clinical settings, usually only a certain number of slices of brain CE-MRI with a large slice gap, not 3D volume, are acquired and available. A 3D model is difficult to construct with such sparse data. Hence, the proposed method is based on 2D slices. The brain T1-weighed CE-MRI dataset was acquired from Nanfang Hospital, Guangzhou, China, and General Hospital, Tianjing Medical University, China, from 2005 to 2010. We collected 3064 slices from 233 patients, containing 708 meningiomas, 1426 gliomas, and 930 pituitary tumors. The images have an in-plane resolution of 512×512 with pixel size 0.49×0.49 mm2. The slice thickness is 6 mm and the slice gap is 1 mm. The tumor border was manually delineated by three experienced radiologists. Four examples are illustrated in Fig 1.
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