Serum NfL Quantification Using Simoa Assay

Serum NfL levels were measured using the Simoa^® assay (NF-LIGHT, Quanterix) performed at the University of Basel, Switzerland. Assay techniques and principles have been previously described.⁹ (link)

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Yeo T., Probert F., Sealey M., Saldana L., Geraldes R., Höckner S., Schiffer E., Claridge T.D., Leppert D., DeLuca G., Kuhle J., Palace J, & Anthony D.C. (2021). Objective biomarkers for clinical relapse in multiple sclerosis: a metabolomics approach. Brain Communications, 3(4), fcab240.

Publication 2021

Simoa® (NF-LIGHT

Assay Light Serum

Corresponding Organization : John Radcliffe Hospital

Other organizations : National Neuroscience Institute, Duke-NUS Medical School, University Hospital of Basel, University of Basel

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Variable analysis

independent variables

None explicitly mentioned

dependent variables

Serum NfL levels

control variables

None explicitly mentioned

controls

No positive or negative controls were explicitly mentioned in the provided information.

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