Glioma Tissue Microarray Repository

Formalin-fixed, paraffin-embedded (FFPE) gliomas were retrieved from pathology archives. Deidentified tissue microarrays (TMAs) were constructed from the gliomas. Three 2-mm diameter cores per tumor were obtained, with each core embedded in a separate TMA block. A total of 104 cases comprised the TMAs, including 9 nonneoplastic controls (cortical dysplasias), 9 grade II astrocytomas, 11 grade III astrocytomas, 12 anaplastic oligodendrogliomas, 16 grade II oligodendrogliomas, and 47 grade IV glioblastomas (GBMs).
Deidentified fresh glioma specimens were prospectively banked via snap-freezing in liquid nitrogen at the time of surgery. Each case was annotated with the corresponding pathologic diagnosis and IDH1/2 mutation status.

Partial Protocol Preview
This section provides a glimpse into the protocol.
The remaining content is hidden due to licensing restrictions, but the full text is available at the following link: Access Free Full Text.

Gilbert M.R., Liu Y., Neltner J., Pu H., Morris A., Sunkara M., Pittman T., Kyprianou N, & Horbinski C. (2013). Autophagy and Oxidative Stress in Gliomas with IDH1 Mutations. Acta neuropathologica, 127(2), 221-233.

Publication 2013

Anaplastic oligodendrogliomas Cortical dysplasias Diagnosis Formalin Glioblastomas Glioma Grade ii astrocytomas Grade iii astrocytomas Microarrays Mutation Nitrogen Oligodendrogliomas Paraffin Tissue Tumor

Corresponding Organization :

Other organizations : University of Kentucky

Top 5 similar protocols

Protocol cited in 6 other protocols

Variable analysis

independent variables

Glioma grade (Grade II astrocytomas, Grade III astrocytomas, Anaplastic oligodendrogliomas, Grade II oligodendrogliomas, Grade IV glioblastomas (GBMs))
IDH1/2 mutation status

dependent variables

Not explicitly mentioned

control variables

Cortical dysplasias (as nonneoplastic controls)

controls

Positive control: Cortical dysplasias
Negative control: Not explicitly mentioned

Annotations

Based on most similar protocols

Etiam vel ipsum. Morbi facilisis vestibulum nisl. Praesent cursus laoreet felis. Integer adipiscing pretium orci. Nulla facilisi. Quisque posuere bibendum purus. Nulla quam mauris, cursus eget, convallis ac, molestie non, enim. Aliquam congue. Quisque sagittis nonummy sapien. Proin molestie sem vitae urna. Maecenas lorem.

As authors may omit details in methods from publication, our AI will look for missing critical information across the 5 most similar protocols.

About PubCompare

Our mission is to provide scientists with the largest repository of trustworthy protocols and intelligent analytical tools, thereby offering them extensive information to design robust protocols aimed at minimizing the risk of failures.

We believe that the most crucial aspect is to grant scientists access to a wide range of reliable sources and new useful tools that surpass human capabilities.

However, we trust in allowing scientists to determine how to construct their own protocols based on this information, as they are the experts in their field.

Ready to get started?

Revolutionizing how scientists
search and build protocols!