KXS comprised Ginseng Radix, Poria, Radix Polygalae, and Acorus Tatarinowii Rhizoma mixed in a ratio of 3:3:2:2 by weight. KXS was obtained via extraction as described previously (Liu et al., 2014 (link)). Briefly, KXS was refluxed and extracted three times with a 10-fold quantity of 60% ethanol, each for 1.5 h. The extracts were dried under a vacuum and stored at −20°C for later use.
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