Each patient referred for PCa management underwent mpMRI of the prostate at 3 Tesla (Achieva; Phillips Healthcare) with endorectal coil (BPX-30; Medrad, Pittsburgh, PA) and 16-channel cardiac surface coil (SENSE; Phillips Healthcare), as previously described (15 (link)). mpMRI sequences consisted of triplanar T2-weighted, diffusion weighted imaging (DWI), apparent diffusion coefficient (ADC) mapping, and dynamic contrast enhancement (DCE). Two radiologists identified prostatic lesions and assigned suspicion levels for PCa based on a previously validated in-house scoring system (SS) and, when available, the prostate imaging reporting and data system (PIRADS) version 2 scoring system. Each FB session consisted of a SB and targeted biopsy of any detectable lesions (at least two targeted cores per lesion) as described previously.(16 (link)) All biopsies were performed by a single urologist or interventional radiologist with more than 10 years’ experience.
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Multiparametric MRI-Guided Prostate Biopsy
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Corresponding Organization : Center for Cancer Research
Other organizations : Johannes Gutenberg University Mainz, University Medical Center of the Johannes Gutenberg University Mainz
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Variable analysis
independent variables
- MpMRI of the prostate at 3 Tesla (Achieva; Phillips Healthcare) with endorectal coil (BPX-30; Medrad, Pittsburgh, PA) and 16-channel cardiac surface coil (SENSE; Phillips Healthcare)
- MpMRI sequences consisting of triplanar T2-weighted, diffusion weighted imaging (DWI), apparent diffusion coefficient (ADC) mapping, and dynamic contrast enhancement (DCE)
- Radiologists identifying prostatic lesions and assigning suspicion levels for PCa based on a previously validated in-house scoring system (SS) and, when available, the prostate imaging reporting and data system (PIRADS) version 2 scoring system
- Measured outcomes related to the detection and evaluation of prostatic lesions and the diagnosis of prostate cancer (PCa)
- All biopsies were performed by a single urologist or interventional radiologist with more than 10 years' experience
- No positive or negative controls were explicitly mentioned in the provided information.
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