Tamoxifen injection was performed largely as previously described [74 (link)]. Tamoxifen (Thermo Scientific, Dreieich, Germany; #J63509.03) was dissolved in Miglyol 812 (Caesar & Lorentz GmbH, Hilden Germany; #CSLO3274.1000) at a concentration of 10 mg/mL. For induction of Cre-ER(T2), mice were either injected with Tamoxifen or solvent alone. Each mouse of the experimental group received four consecutive intraperitoneal Tamoxifen injections, one per day, at a dose of 100 mg/kg body weight. Control mice were injected using the same schedule with Miglyol 812.
Free full text: Click here
