Splenic lymphoma cells from plck-GAPDH mice were injected intravenously into recipient NSG mice. Fourteen days after tumor cell injection, lymphoma engrafted NSG mice were treated by IP injection with etomoxir (20 mg/kg, Sigma-Aldrich), an inhibitor of fatty acid oxidation or with vehicle (100 μl PBS/mouse). The treatment regimen consisted in 3 injections per week.
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