Cannabis use quantity was assessed with a single item in each sample. Participants in Sample 1 were asked, “How much cannabis (grams) do you usually use per week?” (1=1 g, 2=2 g, 3=3–5 g, 4=6–8 g, 5=9–12 g, 6=more than 12 g), whereas participants in Sample 2 were asked, “On a typical day when you use cannabis, on average, how many cones, bongs, or joints do you normally have?”
The Cannabis Use Disorder Identification Test-Revised (CUDIT-R16 (link)) is an eight-item self-report questionnaire that assesses problematic cannabis use within the past 6 months (Appendix 1). Items assess consumption frequency, time spent stoned, cannabis abuse (e.g., use in hazardous situations) and cannabis dependence (e.g., not able to stop using, spending a lot of time obtaining, using, or recovering from use), negative consequences of use (e.g., problems with memory and concentration), and intention to cut down or stop use. Scores can range from 1 to 32, with a cut-off score of 13 indicative of a DSM-IV diagnosis of CUD (dependence).16 (link) Criteria for DSM-IV cannabis abuse are met if one or more of four symptoms are endorsed, and for dependence if three or more of seven symptoms are endorsed.
For Sample 1, past-6 month DSM-5 CUD was assessed via a self-report questionnaire derived from the Structured Clinical Interview, Non-Patient Version for DSM-IV (SCID-I-N/P26 ). Consistent with changes for DSM-5 criteria, a positive diagnosis of CUD could have also included withdrawal.19 (link) Though DSM-5 CUD scoring rules were utilized, assessment of CUD in this study did not include craving due to the timing of the study, thus we refer to these modified DSM-5 criteria (i.e., without craving) from here forward as DSM-5-M.
For Sample 2, the presence of past 6 month CUD was established by using an amended version of the Alcohol Use Disorder and Associated Disabilities Interview Schedule (AUDADIS-IV27 (link)) supplemented with questions from the Comprehensive International Diagnostic Interview (CIDI28 (link)) to assess both the presence of craving and, independently, the presence of each of the seven signs and symptoms of cannabis withdrawal relevant to DSM-5, using the withdrawal criteria as specified in the DSM-5 (including withdrawal relief). Consistent with DSM-5 scoring rules, participants in both samples met criteria for CUD if they endorsed two or more symptoms (10 symptoms assessed in Sample 1; 11 symptoms in Sample 2).
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