Primary Testicular Tumor Retrospective Study

This retrospective study was approved by the Ethics Committee of The First Ningbo Hospital (2021RS105). A retrospective analysis of 14 cases of primary testicular tumors confirmed by pathology in our hospital from January 2013 to December 2021. Inclusion criteria: (1) confirmed by histopathology; (2) with complete routine ultrasound and CEUS data; (3) age > 50 years. Exclusion criteria: (1) incomplete data: lack of histological and pathological results, incomplete ultrasound images; (2) received non-steroidal anti-inflammatory drugs, radiotherapy, chemotherapy and other immunotherapy; (3) Elevated AFP or HCG. The age ranged from 51 to 67 years old, with an average of (59.6 ± 5.3) years old. According to the pathological results, they were divided into non-germ cell tumor group (lymphoma and Leydig cell tumor) and germ cell tumor group (seminoma and spermatogenic tumor).

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Xue N., Wang G., Zhang S, & Lu Y. (2023). The value of contrast-enhanced ultrasonography in differential diagnosis of primary testicular germ cell tumors and non-germ cell tumors over 50 years old. Frontiers in Oncology, 13, 1090823.

Publication 2023

Chemotherapy Germ cell tumor Hospital ethics committee Immunotherapy Leydig cell tumor Lymphoma Non steroidal anti inflammatory drugs Radiotherapy Seminoma Spermatogenic Testicular tumors Tumor Ultrasound

Corresponding Organization : Ningbo First Hospital

Other organizations : University of British Columbia

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Variable analysis

independent variables

Tumor type (non-germ cell tumor group vs. germ cell tumor group)

dependent variables

Histopathological confirmation of primary testicular tumors

control variables

Patients with complete routine ultrasound and CEUS data
Patients aged over 50 years
Patients without incomplete data (lack of histological and pathological results, incomplete ultrasound images)
Patients who did not receive non-steroidal anti-inflammatory drugs, radiotherapy, chemotherapy and other immunotherapy
Patients without elevated AFP or HCG

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