Comprehensive Neurodegeneration Biomarker Panel

Primary antibodies against β-secretase (BACE, Cat# 5606), phospho-Tau (p-Tau, Cat# 15013), Tau (Cat# 46687), Catalase (Cat# 12980), NOD-like receptor (NLR) family pyrin domain containing 3 (NLRP3, Cat# 13158), apoptosis-associated speck-like protein containing a caspase recruitment domain (ASC, Cat# 67824), Caspase-1 (Cat# 3866), Bcl-2-associated X protein (Bax, Cat# 2772), B-cell lymphoma 2 (Bcl-2, Cat# 3498), cleaved caspase-9 (Cat# 20750), cleaved caspase-3 (Cat# 9664), cleaved poly (ADP-ribose) polymerase (PARP, Cat# 5625), FUN14 Domain-Containing 1 (FUNDC1, Cat# 49240), PTEN-induced putative kinase 1 (PINK1, Cat# 6946), Parkin (Cat# 4211), Beclin1 (Cat# 3495), microtubule-associated protein 1A/1B-light chain 3B (LC3B, Cat# 3868), p-cAMP response element-binding (p-CREB, Cat# 9198), CREB (Cat# 9197), choline acetyltransferase (ChAT, Cat# 27269), p-extracellular signal-regulated kinase (p-ERK, Cat# 4377), ERK (Cat# 4695), and β-actin (Cat# 8457) were obtained from Cell Signaling Technology (Danvers, MA, USA). Superoxide dismutase-1 (SOD-1, Cat# sc-515404), SOD-2 (Cat# sc-137254), β-amyloid (Aβ_1–42, Cat# sc-28365), glutathione peroxidase-1 (GPx-1, Cat# sc-133160), glutathione reductase (GR, Cat# sc-133245), and acetylcholinesterase (AChE, Cat# sc-373901) were purchased from Santa Cruz Biotechnology (Santa Cruz, CA, USA). Nitric oxide synthase (iNOS, Cat# PA1-036) was obtained from Invitrogen Life Technologies (Carlsbad, CA, USA). Tumor necrosis factor α (TNFα, Cat# ab66579), IL-6 (Cat# ab9324), interleukin-1β (IL-1β, Cat# ab9722), and anti-brain-derived neurotrophic factor (BDNF, Cat# ab108319) were purchased from Abcam Inc. (Cambridge, CA, USA). Horseradish peroxidase (HRP)-linked anti-rabbit IgG and HRP-linked anti-mouse IgG antibodies were purchased from GenDEPOT (Barker, TX, USA).

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Kim H.L., Lee S.K., Min D.E., Bastola T., Chang B.Y., Bae J.H, & Lee D.R. (2023). Effects of Scrophularia buergeriana Extract (Brainon®) on Aging-Induced Memory Impairment in SAMP8 Mice. Current Issues in Molecular Biology, 45(2), 1287-1305.

Publication 2023

Acetylcholinesterase Ache Actin Amyloid Anti igg Antibodies Apoptosis B cell lymphoma Bcl 2 Bcl 2 associated x protein Beclin1 Brain derived neurotrophic factor Caspase 1 Caspase 3 Caspase 9 Caspase recruitment domain Catalase Choline acetyltransferase Extracellular signal regulated kinase Glutathione peroxidase 1 Glutathione reductase Horseradish peroxidase Il 1β Inos Interleukin 1β Kinase Light Microtubule associated protein 1b Mouse Nitric oxide synthase Nod like receptor P element Parkin Poly adp ribose polymerase Protein Pten Pyrin domain Rabbit Secretase Superoxide dismutase 1 Tnfα

Corresponding Organization :

Other organizations : Wonkwang University

Top 5 similar protocols

Variable analysis

independent variables

Primary antibodies against β-secretase (BACE, Cat# 5606)
Primary antibodies against phospho-Tau (p-Tau, Cat# 15013)
Primary antibodies against Tau (Cat# 46687)
Primary antibodies against Catalase (Cat# 12980)
Primary antibodies against NOD-like receptor (NLR) family pyrin domain containing 3 (NLRP3, Cat# 13158)
Primary antibodies against apoptosis-associated speck-like protein containing a caspase recruitment domain (ASC, Cat# 67824)
Primary antibodies against Caspase-1 (Cat# 3866)
Primary antibodies against Bcl-2-associated X protein (Bax, Cat# 2772)
Primary antibodies against B-cell lymphoma 2 (Bcl-2, Cat# 3498)
Primary antibodies against cleaved caspase-9 (Cat# 20750)
Primary antibodies against cleaved caspase-3 (Cat# 9664)
Primary antibodies against cleaved poly (ADP-ribose) polymerase (PARP, Cat# 5625)
Primary antibodies against FUN14 Domain-Containing 1 (FUNDC1, Cat# 49240)
Primary antibodies against PTEN-induced putative kinase 1 (PINK1, Cat# 6946)
Primary antibodies against Parkin (Cat# 4211)
Primary antibodies against Beclin1 (Cat# 3495)
Primary antibodies against microtubule-associated protein 1A/1B-light chain 3B (LC3B, Cat# 3868)
Primary antibodies against p-cAMP response element-binding (p-CREB, Cat# 9198)
Primary antibodies against CREB (Cat# 9197)
Primary antibodies against choline acetyltransferase (ChAT, Cat# 27269)
Primary antibodies against p-extracellular signal-regulated kinase (p-ERK, Cat# 4377)
Primary antibodies against ERK (Cat# 4695)
Primary antibodies against Superoxide dismutase-1 (SOD-1, Cat# sc-515404)
Primary antibodies against SOD-2 (Cat# sc-137254)
Primary antibodies against β-amyloid (Aβ_1–42, Cat# sc-28365)
Primary antibodies against glutathione peroxidase-1 (GPx-1, Cat# sc-133160)
Primary antibodies against glutathione reductase (GR, Cat# sc-133245)
Primary antibodies against acetylcholinesterase (AChE, Cat# sc-373901)
Primary antibodies against nitric oxide synthase (iNOS, Cat# PA1-036)
Primary antibodies against tumor necrosis factor α (TNFα, Cat# ab66579)
Primary antibodies against IL-6 (Cat# ab9324)
Primary antibodies against interleukin-1β (IL-1β, Cat# ab9722)
Primary antibodies against brain-derived neurotrophic factor (BDNF, Cat# ab108319)

dependent variables

Levels of β-secretase (BACE)
Levels of phospho-Tau (p-Tau)
Levels of Tau
Levels of Catalase
Levels of NOD-like receptor (NLR) family pyrin domain containing 3 (NLRP3)
Levels of apoptosis-associated speck-like protein containing a caspase recruitment domain (ASC)
Levels of Caspase-1
Levels of Bcl-2-associated X protein (Bax)
Levels of B-cell lymphoma 2 (Bcl-2)
Levels of cleaved caspase-9
Levels of cleaved caspase-3
Levels of cleaved poly (ADP-ribose) polymerase (PARP)
Levels of FUN14 Domain-Containing 1 (FUNDC1)
Levels of PTEN-induced putative kinase 1 (PINK1)
Levels of Parkin
Levels of Beclin1
Levels of microtubule-associated protein 1A/1B-light chain 3B (LC3B)
Levels of p-cAMP response element-binding (p-CREB)
Levels of CREB
Levels of choline acetyltransferase (ChAT)
Levels of p-extracellular signal-regulated kinase (p-ERK)
Levels of ERK
Levels of Superoxide dismutase-1 (SOD-1)
Levels of SOD-2
Levels of β-amyloid (Aβ_1–42)
Levels of glutathione peroxidase-1 (GPx-1)
Levels of glutathione reductase (GR)
Levels of acetylcholinesterase (AChE)
Levels of nitric oxide synthase (iNOS)
Levels of tumor necrosis factor α (TNFα)
Levels of IL-6
Levels of interleukin-1β (IL-1β)
Levels of brain-derived neurotrophic factor (BDNF)

control variables

Horseradish peroxidase (HRP)-linked anti-rabbit IgG
Horseradish peroxidase (HRP)-linked anti-mouse IgG

Annotations

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