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Antibody-Conjugated mRNA Lipid Nanoparticles

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Parhiz H., Shuvaev V.V., Pardi N., Khoshnejad M., Kiseleva R.Y., Brenner J.S., Uhler T., Tuyishime S., Mui B.L., Tam Y.K., Madden T.D., Hope M.J., Weissman D, & Muzykantov V.R. (2018). PECAM-1 directed re-targeting of exogenous mRNA providing two orders of magnitude enhancement of vascular delivery and expression in lungs independent of apolipoprotein E-mediated uptake. Journal of controlled release : official journal of the Controlled Release Society, 291, 106-115.
Publication 2018
Acceleration Antibodies Antibody Assay Buffer Capillary Carbon Cells Copper G protein Gel filtration Hydrodynamic Hydroxylamine Isotype Laser doppler velocimetry Lipid nanoparticles Maleimide Mrna Nacl Paper Pecam 1 Post technique Sata Sephadex Sepharose cl 4b Stain Sulfhydryl group Thioether Transmission electron microscope Uranyl acetate

Corresponding Organization : University of Pennsylvania

Other organizations : Acuitas Therapeutics (Canada)

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