Investigating Lipid-Mediated Cell Signaling

Sources for chemicals used in this study: Amitriptyline (Sigma Aldrich, Steinheim, Germany), BAPTA AM (Merck, Darmstadt, Germany), ceramide C16:0 and ceramide C24:1 (Cayman Chemical, Ann Arbor, MI, USA), DMSO (Sigma Aldrich), dodecane (Thermo Fisher Scientific, Waltham, MA, USA), ethanol (VWR, Radnor, PA, USA), fumonisin B1 (Cayman Chemical), hydrogen peroxide 3% (Sigma Aldrich), PDMP (Enzo Life Sciences, Farmingdale, NY, USA), 4-phenylbutyrate (Cayman Chemical, Ann Arbor, MI, USA), ryanodine (Santa Cruz, Dallas, TX, USA), sodium nitrite (Sigma Aldrich).

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Zimmermann T., Staebler S., Taudte R.V., Ünüvar S., Grösch S., Arndt S., Karrer S., Fromm M.F, & Bosserhoff A.K. (2023). Cold Atmospheric Plasma Triggers Apoptosis via the Unfolded Protein Response in Melanoma Cells. Cancers, 15(4), 1064.

Publication 2023

Amitriptyline BAPTA AM ceramide C24:1 DMSO dodecane ethanol fumonisin B1 hydrogen peroxide 3% ryanodine sodium nitrite

4 phenylbutyrate Amitriptyline Bapta Cayman Ceramide Ceramide c16 Dmso Dodecane Ethanol Fumonisin b1 Hydrogen 3 Hydrogen peroxide Pdmp Peroxide Ryanodine Sodium nitrite

Corresponding Organization : Comprehensive Cancer Center Erlangen

Other organizations : Philipps University of Marburg, Goethe University Frankfurt, University Hospital Regensburg

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Variable analysis

independent variables

Amitriptyline
BAPTA AM
Ceramide C16:0
Ceramide C24:1
Dodecane
Ethanol
Fumonisin B1
Hydrogen peroxide 3%
4-phenylbutyrate
Ryanodine
Sodium nitrite

dependent variables

Not explicitly mentioned

control variables

Not explicitly mentioned

controls

Positive controls: Not specified
Negative controls: Not specified

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