Twelve week old female wild-type (WT; C57BL/6 J), CCR2 knockout (CCR2−/−)43 (link), Cx3cr1GFP/+ 44 (link), Cx3cr1CreERT2 45 (link), Rosa26-LSL-YFP46 (link), PLPCreERT2 47 (link), Rpl22HA 24 (link), PLPCreERT2 47 (link), iDTR48 (link) and their littermate controls were used. All lines were bred and maintained at the KU Leuven animal facility on a 12:12-h light-dark cycle and had ad libitum access to tap water and commercially available chow (ssniff® R/M-H, ssniff Spezialdiäten GmbH). All experimental procedures were approved by the Animal Care and Animal Experiments Ethical Committee of KU Leuven.
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