Regional Cerebral Blood Flow Analysis

CBF values and images were calculated using a basis function implementation of the single-tissue compartment model [34 (link)–36 (link)], as implemented in the Turku PET Centre library tools [37 ], using either the BSIF or IDIF as input function. Only the first 5 min of the acquisition were used. Regional cerebral blood flow (rCBF) values were extracted for all regions as defined using the Hammers atlas [38 (link)] after spatial normalisation to a common MNI (ICBM 152 [39 (link), 40 (link)]) space using FSL [41 (link), 42 ] (Additional file 1: Fig. S1).

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Young P., Appel L., Tolf A., Kosmidis S., Burman J., Rieckmann A., Schöll M, & Lubberink M. (2023). Image-derived input functions from dynamic 15O–water PET scans using penalised reconstruction. EJNMMI Physics, 10, 15.

Publication 2023

Library Regional cerebral blood flow Tissue

Corresponding Organization :

Other organizations : University of Gothenburg, Uppsala University, Umeå University

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Variable analysis

independent variables

Input function (BSIF or IDIF)

dependent variables

Regional cerebral blood flow (rCBF) values

control variables

Only the first 5 min of the acquisition were used
Spatial normalisation to a common MNI (ICBM 152) space using FSL

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