Blood samples will be collected before surgery as part of regular medical care. No blood draw will be done specifically for this study. An additional volume of blood will be collected in two 5 ml serum separator tubes and seven 5 ml EDTA tubes and transported to the laboratories to be processed.
Tumor samples will be collected during surgery as part of regular medical care and sent to the pathology laboratory. The surplus tissue (including tumor and adjacent normal tissues) not required for diagnosis will be transported to the laboratory in vials containing medium supplemented in antibiotics and ROCK inhibitor Y-27632.
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