We carried out partial correlation analyses to investigate associations of hippocampal rGMVs with visual and auditory attention-related clinical variables [covariates: age, sex, total intracranial volume (TIV), and IQ].
A threshold false discovery rate (FDR) = 0.2 was determined to be significant for addressing multiple comparison issues (i.e., FDR = 0.2 or less for significance) (Genovese et al., 2002 (link)). Only among brain areas showing significance does FDR thresholding optimize the expected proportion of false positives (Genovese et al., 2002 (link)). FDR levels in the range of 0.1–0.2 are practically and originally known to be acceptable, as they have been applied in several neuroimaging studies (Genovese et al., 2002 (link); Molteni et al., 2017 (link); Gordon et al., 2018 (link); Yu et al., 2018 (link); Jung et al., 2019 (link)). All statistical analyses were performed using SPSS 20.0 for Windows (SPSS Inc., Chicago, IL, USA) and MATLAB-based custom software (MathWorks, Sherborn, MA, USA).
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