We present a retrospective analysis of collected data. Patients who underwent their first kidney transplantation in Beijing Chaoyang Hospital from August 7, 2016 to July 30, 2018 and met the inclusion criteria were included in the study. All kidneys of DCD kidney transplantation in this study were procured from donation after citizens’ death, adhering to the guidelines of the National Program for Deceased Organ Donation in China. Data on donor characteristics, recipient characteristics, number of DGFs, and outcomes at the 3-year follow-up visit were obtained from the electronic medical records. Cohort generation is shown in Figure 1. The inclusion criteria were: (1) grafts obtained from DCD, (2) surgery performed as single-kidney transplantation for allografts with a single renal artery, and (3) recipients older than 16 years during the study period. The exclusion criteria were: (1) recipients who did not have at least 1 biomarker measured, and (2) recipients who lacked medical records for 3 years after surgery due to death or loss to follow-up. Patients were followed with blood test and urine analysis every 3 weeks for a period of 3 months, every 2 weeks thereafter until 9 months, and then monthly. DGF was defined as “dialysis is needed within 1 week after kidney transplantation,” and the diagnosis of DGF was assessed by 2 independent transplant surgeons. The eGFR was calculated using the abbreviated Modification of Diet in Renal Disease (MDRD) equation. The formula used for eGFR was as follows:
Serum creatinine reduction ratio (CRR) was defined as “the average percentage of creatinine reduction within 3 days after kidney transplantation as compared to the previous day.” The formula used for CRR was as follows: