Characterization of Neutrophil CKA

Example 16

Demonstrating CKA of CD34+ Stem Cell Derived Neutrophils (SCDNs)

Results were obtained via the xCELLigence assay with further populations of CD34+ Stem Cell Derived Neutrophils (FIG. 6), and were consistent with results obtained via the MTT assay as described above. SCDNs (generated ex vivo) were again shown to have differential CKA, with culture 5 representing low CKA neutrophils and culture 1 representing high CKA neutrophils.

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US11878033B2. Cancer-killing cells (2024-01-23). LIFT BIOSCIENCES LTD [GB]. Inventors: Alex Blyth [GB], Nico Bruyniks [GB].

Patent 2024

Assay Cancer Cells Neutrophils Populations Stem cell

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Variable analysis

independent variables

Culture 5 (low CKA neutrophils)
Culture 1 (high CKA neutrophils)

dependent variables

Cytokine-induced killer activity (CKA) of CD34+ stem cell derived neutrophils (SCDNs)

control variables

Control variables not explicitly mentioned

controls

None specified
None specified

Annotations

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