Heart function, liver function, and renal function were access by measuring serum creatine kinase (Creatine kinase Assay Kit, A032-1-1), lactate dehydrogenase (Lactate dehydrogenase Assay Kit, A020-2-2), alanine aminotransferase (Alanine aminotransferase Assay Kit, C009-2-1), aspartate aminotransferase (Aspartate aminotransferase Assay Kit, C010-2-1), and creatinine (Creatinine Assay Kit, C011-2-1) using the commercial kits obtained from Nanjing Jiancheng Bioengineering Institute (Nanjing, China).