Echocardiographic Evaluation of Murine Cardiac Function

A Vevo 3100 High-Resolution Imaging System (VisualSonics Inc, Toronto, Canada) was used to perform the echocardiography in the mice (Kumar et al., 2019b (link)). Mice were sedated under 2% isoflurane and their heart rate was maintained at 450 ± 20 beats per minute. Short axis B- and M-mode 2D echocardiograms were recorded through the anterior and posterior LV walls at the level of the papillary muscle. Fractional shortening (FS) and ejection fraction (EF) were calculated by the VisualSonics Measurement Software.

Free full text: Click here

Kumar A., Belhaj M., DiPette D.J, & Potts J.D. (2021). A Novel Alginate-Based Delivery System for the Prevention and Treatment of Pressure-Overload Induced Heart Failure. Frontiers in Pharmacology, 11, 602952.

Publication 2020

Vevo 3100 High-Resolution Imaging System

Axis Echocardiograms Heart rate Isoflurane Mice Papillary muscle

Corresponding Organization : University of South Carolina

Top 5 similar protocols

Variable analysis

independent variables

Type of mice

dependent variables

Fractional shortening (FS)
Ejection fraction (EF)

control variables

Isoflurane concentration (2%)
Heart rate (450 ± 20 beats per minute)

controls

No positive or negative controls were explicitly mentioned in the provided information.

Annotations

Based on most similar protocols

Etiam vel ipsum. Morbi facilisis vestibulum nisl. Praesent cursus laoreet felis. Integer adipiscing pretium orci. Nulla facilisi. Quisque posuere bibendum purus. Nulla quam mauris, cursus eget, convallis ac, molestie non, enim. Aliquam congue. Quisque sagittis nonummy sapien. Proin molestie sem vitae urna. Maecenas lorem.

As authors may omit details in methods from publication, our AI will look for missing critical information across the 5 most similar protocols.

About PubCompare

Our mission is to provide scientists with the largest repository of trustworthy protocols and intelligent analytical tools, thereby offering them extensive information to design robust protocols aimed at minimizing the risk of failures.

We believe that the most crucial aspect is to grant scientists access to a wide range of reliable sources and new useful tools that surpass human capabilities.

However, we trust in allowing scientists to determine how to construct their own protocols based on this information, as they are the experts in their field.

Ready to get started?

Revolutionizing how scientists
search and build protocols!