Comparative Evolutionary Analysis of Monkeypox Virus

The mPox viral protein sequence was retrieved as a FASTA file from the UniProt database (https://www.uniprot.org/) [21 (link)] by searching with the keyword “monkeypox cell surface binding protein.” Following that, we used our target sequence as the query sequence to analyze the BLASTp program [22 (link)] for evaluating phylogenetic information from the NCBI database (https://www.ncbi.nlm.nih.gov). Finally, in order to better understand the comparative evolution of the organisms, a phylogenetic tree was constructed and visualized using the Microreact database (https://microreact.org/) [23 (link)].

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Mazumder L., Hasan M.R., Fatema K., Begum S., Azad A.K, & Islam M.A. (2023). Identification of B and T Cell Epitopes to Design an Epitope-Based Peptide Vaccine against the Cell Surface Binding Protein of Monkeypox Virus: An Immunoinformatics Study. Journal of Immunology Research, 2023, 2274415.

Publication 2023

Cell surface protein Evolution Monkeypox Mpox Protein sequence Viral protein

Corresponding Organization : Jagannath University

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Variable analysis

independent variables

Sequence analysis of the mPox viral protein using the BLASTp program

dependent variables

Phylogenetic information obtained from the NCBI database
Phylogenetic tree constructed and visualized using the Microreact database

control variables

Not explicitly mentioned

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