Mature miRs Expression in Breast Cancer

Mature miRs expression in primary tumors of BCPs was obtained from the TCGA Breast Cancer (BRCA) cohort available in the UCSC Xena bioinformatics tool (26 (link)). Mature miR strand expression RNAseq (IlluminaHiSeq) data from 16 BCPs (invasive ductal breast carcinoma, clinical stage III-A, -B and –C, luminal type A) samples paired with 56 normal breast tissues were included in the analysis. We evaluated a pool of miRs involved in the regulation of monocyte differentiation to pre-OC: miR-21 (MIMAT0000076), miR-29 family (MIMAT0000086), miR-100-5p (MIMAT0000098), miR -26a (MIMAT0000082), miR-125a (MIMAT0000443), miR-145 (MIMAT0000437), miR-214 (MIMAT0000271), miR-218 (MIMAT0000275), miR-301b (MIMAT0004958) and miR-365 (MIMAT0000710); fusion of pre-OC to inactive OC: miR-7b (MIMAT0004553) and miR-30a (MIMAT0000087) and regulation of OC function, survival and apoptosis: miR-17 (MIMAT0000070), miR-106b (MIMAT0000680), miR-27a (MIMAT0000084), miR-29b (MIMAT0000100), miR-31 (MIMAT0000089), miR-146a (MIMAT0000449), miR-155 (MIMAT0000646), miR-186 (MIMAT0000456), miR-193-3p (MIMAT0000459) and miR-539 (MIMAT0003163).

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Fernández Vallone V., Borzone F.R., Martinez L.M., Giorello M.B., Choi H., Dimase F., Feldman L., Bordenave R.H., Chudzinski-Tavassi A.M., Batagelj E, & Chasseing N.A. (2023). Spontaneous Osteoclastogenesis, a risk factor for bone metastasis in advanced luminal A-type breast cancer patients. Frontiers in Oncology, 13, 1073793.

Publication 2023

Apoptosis Breast Breast cancer Invasive ductal breast carcinoma Luminal Monocyte Normal tissues Tumors

Corresponding Organization : Experimental Medicine and Biology Institute

Other organizations : Cornell University, Central Texas Veterans Health Care System, Universidad Nacional del Centro de la Provincia de Buenos Aires, Instituto Butantan

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Mature miRs expression in primary tumors of BCPs

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