We formulated the prediction of dementia as a binary classification problem (dementia, control); therefore, evaluation metrics, such as accuracy, F1-score, balanced accuracy, precision, specificity and sensitivity, were used to measure the performance of the subsets of features. The following evaluation metrics were used:

True positives (TP): number of dementia cases that were correctly classified.

False positives (FP): number of healthy subjects incorrectly classified as dementia cases.

True negatives (TN): number of healthy subjects correctly classified.

False negatives (FN): number of dementia cases incorrectly classified as healthy subjects.

Accuracy (%): the proportion of correct classifications among total classifications:

Accuracy=TP+TNn
where n is the number of total classifications per test.

Sensitivity (%): The proportion of correctly classified dementia cases.

Sensitivity=TPTP+FN

Specificity (%): The proportion of correctly classified healthy subjects.

Specificity=TNTN+FP

Precision: The proportion of subjects classified as dementia cases who have dementia.

Precision=TPTP+FP

F1-score (F-measure) (%): Harmonic mean of precision and sensitivity.

F1=2×Sensitivity×PrecisionSensitivity+Precision=TPTP+FP+FN/2
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