The follow-up plan was divided into two methods: telephone and outpatient follow-up, and Internet APP and WeChat follow-up. In principle, telephone follow-ups should be conducted once a month for the enrolled patients. The follow-up should include answering the patients’ questions about sublingual medication, reminding them about the medication, and asking them about the use of symptomatic medication and their rhinitis symptoms. An outpatient follow-up visit should be conducted every 3 months. The follow-up content is the same as above, and the patient should be given a continuation of the prescription. Also, the latest knowledge about AR and precautions for SLIT should be popularized on the Internet APP. The symptom and medication questionnaire survey were conducted through the Internet APP to follow up on the improvement of symptoms and medications of the children and monitor the adverse drug reactions to guide parents in their use of the drugs. A WeChat group should also be established, through which regular health lectures on AR can be given. We can also listen to the feedback of the children’s parents, follow up on symptoms and medication, promote communication and interaction between families, and further enhance compliance.