The Methods section is divided into three subsections. In the first, lipid molecule and atom names are briefly reviewed to avoid confusion among several commonly used conventions. Section 2.2 describes the QM methods used in justifying modifications to the partial charges for certain atoms in the head group of the lipid molecules along with the optimization procedure used to produce optimized non-bond parameters for the ester moieties in the glycerol linker region. This subsection also describes the QM methods used to obtain highly accurate torsional profiles for certain head group and alkene dihedrals. The Section 2.3 describes the methods used in the molecular dynamics (MD) simulations. The C36 additive all-atom lipid force field may be downloaded from the MacKerell group web page at http://mackerell.umaryland.edu/CHARMM_ff_params.html.