Baseline [18F]FDG-PET/CT Imaging Protocol for NCRT Patients

The patients underwent [18F]FDG-PET/CT for baseline staging before NCRT. Before imaging, the patients fasted for at least 4 h to reduce the effect of serum glucose [12 (link)]. Approximately 60 min after 370 MBq of [18F]FDG was administered to the patients, images were taken using a PET/CT scanner (Discovery STE 16-Slice PET/CT Scanner, GE Healthcare, Milwaukee, WI, USA). The patients were required to rest during the uptake period. A CT topogram was used to label the axial scan range. After the CT was performed, PET images were obtained in the three-dimensional acquisition mode at 2 min per field of view (FOV) with an 11-slice overlap at the borders of the FOV. The CT performed was a low-dose non-contrast CT.
The [18F]FDG-PET data were saved in Advantage Workstation (Ver. 4.4, GE Healthcare). Two nuclear medicine physicians reviewed the images and located the target lesions. The PET/CT workstation quantified [18F]FDG uptake automatically.

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Wu K.C., Chen S.W., Hsieh T.C., Yen K.Y., Law K.M., Kuo Y.C., Chang R.F, & Kao C.H. (2021). Prediction of Neoadjuvant Chemoradiotherapy Response in Rectal Cancer with Metric Learning Using Pretreatment 18F-Fluorodeoxyglucose Positron Emission Tomography. Cancers, 13(24), 6350.

Publication 2021

Discovery STE 16-Slice PET/CT Scanner Advantage Workstation

18f fdg Ct scanner Glucose Nuclear medicine Patients Pet ct Physicians Serum

Corresponding Organization : Asia University

Other organizations : Taipei Medical University, National Chung Hsing University

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Variable analysis

independent variables

Fasting for at least 4 hours before imaging

dependent variables

[18F]FDG uptake in target lesions

control variables

Patients resting during the uptake period
Low-dose non-contrast CT performed

controls

No positive or negative controls were explicitly mentioned in the provided information.

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