Multimodal MRI Acquisition Protocol

MRI data were continuously collected on a Siemens Prisma^fit 3T MRI scanner using a standard 20-channel coil at the Beijing MRI Center for Brain Research of the Chinese Academy of Sciences. Functional MRI time series data were acquired using a multiband BOLD-sensitive T2^*-weighted gradient echo-planar-imaging (EPI) sequence (Moeller et al., 2010 (link)) (TR = 1,000 ms, TE = 30 ms, slices thickness = 2.2 mm, in-plane resolution = 2.2 × 2.2 mm, flip angle = 45°, phase encoding direction = AP, multiband acceleration factor = 4). Sixty-four axial slices covering the whole brain were collected using interleaved multislice mode in the ascending direction. Six “dummy” scans were acquired and then discarded by the scanners. High-spatial-resolution anatomical images were acquired using a T1-weighted, magnetization-prepared rapid acquisition gradient echo (MPRAGE) sequence (TR = 2,200 ms, TE = 2.08 ms, slice thickness = 1 mm, in-plane resolution = 1.0 × 1.0 mm and flip angle = 8°). Fat suppression was applied for T1 acquisition.