Preoperative and postoperative medical care was the same for both groups of patients, except for the different surgical procedures. Appropriate medical treatment included blood glucose regulation, perfusion improvement by prostaglandins or antiplatelet drugs, appropriate antibiotics administration, and routine sterile dressing change. Tissue samples were taken for microbiological analysis. Sensitive antibiotics were selected for intravenous application according to the results of drug susceptibility test. It was switched to oral therapy when the patients was clinically improving. During the treatment period, blood glucose was monitored daily, and oral hypoglycemic drugs, such as metformin, acarbose, etc., were used. To control blood glucose, subcutaneous injection of short-acting and long-acting insulin were applied, and the dose was dynamically adjusted until the wound healed.
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