Muscimol Preparation and Dosing

Muscimol (R&D systems, Minneapolis, Minnesota) was dissolved in saline (0.9%) to produce 0.5 mM Muscimol. Doses were chosen based on previous work (Jaramillo, Randall, Frisbee, & Besheer, 2016 (link); Randall et al., 2021 (link)) and our own pilot studies.

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Ornelas L.C., Van Voorhies K, & Besheer J. (2021). The Role of the Nucleus Reuniens in Regulating Contextual Conditioning with the Predator Odor TMT in Female Rats. Psychopharmacology, 238(12), 3411-3421.

Publication 2021

Muscimol

Muscimol Saline

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Variable analysis

independent variables

Muscimol dose

dependent variables

Measured outcomes

control variables

Saline (0.9%)

controls

Positive controls not explicitly mentioned.
Negative controls not explicitly mentioned.

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