In a 100 mL round bottom flask, 1 equiv of phthalic anhydride and
1 equiv of amine were placed provided with a reflux condenser (Scheme 1 ). Forty milliliters
of glacial acetic acid was added as a solvent. The mixture of reaction
was refluxed with stirring for 1 h at(room temp) so that imide was
synthesized. Glacial acetic acid was eliminated by extracting the
mixture of reaction with water, ethyl acetate, and chloroform. The
crude product was purified using column chromatography giving a yield
of 94–96%.
1 equiv of amine were placed provided with a reflux condenser (
of glacial acetic acid was added as a solvent. The mixture of reaction
was refluxed with stirring for 1 h at(room temp) so that imide was
synthesized. Glacial acetic acid was eliminated by extracting the
mixture of reaction with water, ethyl acetate, and chloroform. The
crude product was purified using column chromatography giving a yield
of 94–96%.
