Non-Invasive Liver Triglyceride Quantification

¹H-MRS spectra were acquired with a 3.0 Tesla MR system (Siemens, Tim Trio, Erlangen, Germany) using a body matrix coil and a spine matrix (Siemens, Erlangen, Germany) as shown previously (14 (link), 15 (link)). Liver spectra were fitted using the AMARES algorithm in the Java-based magnetic resonance user interface (jMRUI) software package (20 (link)). The average of eight spectra was used for liver triglyceride calculation. NAFLD was defined as IHTG ≥5.0% as shown previously in adolescents (3 (link)).

Partial Protocol Preview
This section provides a glimpse into the protocol.
The remaining content is hidden due to licensing restrictions, but the full text is available at the following link: Access Free Full Text.

Lee S., Rivera-Vega M., Alsayed H.M., Boesch C, & Libman I. (2014). Metabolic inflexibility and insulin resistance in obese adolescents with nonalcoholic fatty liver disease. Pediatric diabetes, 16(3), 211-218.

Publication 2014

3.0 Tesla MR system body matrix coil

1h mrs Adolescents Body Liver Magnetic resonance Nafld Spine Triglyceride Trio

Corresponding Organization :

Other organizations : Children's Hospital of Pittsburgh, University of Pittsburgh, University of Bern

Top 5 similar protocols

Variable analysis

independent variables

Magnetic resonance (MR) system (3.0 Tesla, Siemens, Tim Trio, Erlangen, Germany)
Body matrix coil and spine matrix (Siemens, Erlangen, Germany)

dependent variables

Liver triglyceride content
Non-alcoholic fatty liver disease (NAFLD) defined as intrahepatic triglyceride (IHTG) ≥5.0%

control variables

Average of eight spectra used for liver triglyceride calculation
AMARES algorithm in the Java-based magnetic resonance user interface (jMRUI) software package used for liver spectra fitting

controls

Positive control: Not explicitly mentioned.
Negative control: Not explicitly mentioned.

Annotations

Based on most similar protocols

Etiam vel ipsum. Morbi facilisis vestibulum nisl. Praesent cursus laoreet felis. Integer adipiscing pretium orci. Nulla facilisi. Quisque posuere bibendum purus. Nulla quam mauris, cursus eget, convallis ac, molestie non, enim. Aliquam congue. Quisque sagittis nonummy sapien. Proin molestie sem vitae urna. Maecenas lorem.

As authors may omit details in methods from publication, our AI will look for missing critical information across the 5 most similar protocols.

About PubCompare

Our mission is to provide scientists with the largest repository of trustworthy protocols and intelligent analytical tools, thereby offering them extensive information to design robust protocols aimed at minimizing the risk of failures.

We believe that the most crucial aspect is to grant scientists access to a wide range of reliable sources and new useful tools that surpass human capabilities.

However, we trust in allowing scientists to determine how to construct their own protocols based on this information, as they are the experts in their field.

Ready to get started?

Revolutionizing how scientists
search and build protocols!